Centro de Medicina Traslacional (CEMET): Envíos recientes

  • Emotional prosody processing inepilepsy: some insights on brain reorganization 
    Ferrara, Lucy Alba; Kochen, Silvia; Hausmann, Markus (2018-03-13)
    Drug resistant epilepsy is one of the most complex, multifactorial and polygenic neurological syndrome. Besides its dynamicity and variability, it still provides us with a model to study brain-behavior relationship, giving ...
  • Contrasting dynamics of memory consolidation for novel word forms and meanings revealed by behavioral and neurophysiological markers 
    Kaczer, Laura; Bavassi, Luz; Petroni, Agustín; Fernández, Rodrigo S.; Laurino, Julieta; Degiorgi, Sofía; Hochman, Eithan; Forcato, Cecilia; Pedreira, María E. (2018-07-02)
    Learning novel words is a challenging process for our memory systems; we must be able to recall new word forms and meanings in order to communicate. However, the dynamics of the word memory formation is still unclear. Here, ...
  • Sex and Age-Related Differences in Neuroticism and Allostatic Load Index in Urban Patients with General Anxiety Disorder Treated with Alprazolam 
    Soria, Carlos A.; Remedi, Carolina; D`Alessio, Luciana; Roldán, Emilio J. A. (2018-06-19)
    Introduction: Allostatic Load (AL) index proposes indicators for the functioningof the main potentially stress-affected systems. Sex differences instress response and stress-related diseases susceptibility have been ...
  • Morfometría de la fosa posterior durante el desarrollo postnatal temprano 
    Vallejo Azar, Mariana N.; Zurdo, Lucas; Garzón, Nicolás; Higuera, Felipe; Blanco, Yeny; Jaimovich, Roberto; Jaimovich, Sebastián; Rugilo, Carlos; Bendersky, Mariana; González, Paula N. (2018-11-10)
    Introducción: Los defectos en el desarrollo normal de la fosa posterior pueden dar origen a numerosas patologías. Sin embargo no han habido estudios exhaustivos de la morfometría de la fosa durante el desarrollo postnatal ...
  • Brain structural networks in mouse exposed to chronic maternal undernutrition 
    Andrés, Jimena Barbeito (2018-03-29)
    Brain structural connectivity is known to be altered in cases of intrauterine growth restriction and premature birth, although the specific effect of maternal nutritional restriction, a common burden in human populations, ...
  • Description and Analysis of Spatial Patterns in Geometric Morphometric Data 
    Gonzalez, Paula N.; Bonfli, Noelia; Azar, Mariana N. Vallejo; Andres, Jimena Barbeito; Bernal, Valeria; Perez, S. Ivan (2019-05-28)
    The development of techniques for the acquisition of high-resolution 3D images, such as computed tomography and magnetic resonance imaging, has opened new avenues to the study of complex morphologies. Detailed descriptions ...
  • Management of epilepsy in pregnancy: a report from the International League Against Epilepsy Task Force on Women and Pregnancy 
    Tomson, Torbjörn; Battino, Dina; Bromley, Rebecca; Kochen, Silvia; Meador, Kimford; Pennell, Page; Thomas, Sanjeev V. (2020-01-17)
    The risks associated with use of antiepileptic drugs during pregnancy are a major concern for all women with epilepsy with childbearing potential. These risks have to be balanced against foetal and maternal risks associated ...
  • Declining malformation rates with changed antiepileptic drug prescribing 
    Tomson, Torbjorn; Battino, Dina; Bonizzoni, Erminio; Craig, John; Lindhout, Dick; Perucca, Emilio; Sabers, Anne; Thomas, Sanjeev V.; Vajda, Frank (2019-08-27)
    Objective: Changes in prescribing patterns of antiepileptic drugs (AEDs) in pregnant women with epilepsy would be expected to affect the risk of major congenital malformations (MCMs). To test this hypothesis, we analyzed ...
  • Adult-onset psychogenic nonepileptic seizures: A multicenter international study 
    Pooya, Ali A. Asadi; Valente, Kette; Restrepo, Anilu Daza; Alessio, Luciana D'; Homayoun, Maryam; Bahrami, Zahra; Alessi, Rudá; Paytan, Angélica Aroni; Kochen, Silvia; Myers, Lorna; Sawchuk, Tyson; Buchhalter, Jeffrey; Taha, Firas; Lazar, Lorraine M.; Pick, Susannah; Nicholson, Timothy (2019-06-11)
    Purpose: The aim of this multicenter international cross-cultural study was to compare clinical variables in a large sample of people with adult-onset psychogenic nonepileptic seizures (PNES). Methods: In this retrospective ...
  • Depression and Temporal Lobe Epilepsy: Expression Pattern of Calbindin Immunoreactivity in Hippocampal Dentate Gyrus of Patients Who Underwent Epilepsy Surgery with and without Comorbid Depression 
    Alessio, Luciana D’; Konopka, Hector; Solís, Patricia; Scévola, Laura; Lima, Mónica Fernandez; Nuñez, Claudio; Seoane, Eduardo; Oddo, Silvia; Kochen, Silvia (2019-05-02)
    Purpose. Changes in calbindin (CB) expression have been reported in patients with temporal lobe epilepsy (TLE) with controversial implications on hippocampal functions. The aim of this study was to determine the CB ...
  • Region-specific changes in Mus musculus brain size and cell composition under chronic nutrient restriction 
    Andrés, Jimena Barbeito; Fonseca, Emily Castro; Qiu, Lily R.; Bernal, Valeria; Lent, Roberto; Henkelman, Mark; Lukowiak, Kenneth; Gleiser, Pablo M.; Hallgrimsson, Benedikt; Gonzalez, Paula N. (2019-09-05)
    Nutrition is one of the most influential environmental factors affecting the development of different tissues and organs. It is suggested that under nutrient restriction the growth of the brain is spared as a result of the ...
  • Asimetrías en el patrón surcal del opérculo frontoparietal 
    Vallejo Azar, Mariana Nahir; Bouzigues, Arabella; Alba Ferrara, Lucía; González, Paula Natalia; Bendersky, M (2019-11)
    The objective of this study was to evaluate the interhemispheric variation (asymmetries) in the sulcal pattern of the frontoparietal operculum. The study of perisilvian areas anatomical variability is important for clinical ...
  • Transethnic meta-analysis of rare coding variants in PLCG2, ABI3, and TREM2 supports their general contribution to Alzheimer’s disease 
    Dalmasso, Maria Carolina; Brusco, Luis Ignacio; Olivar, Natividad; Muchnik, Carolina; Hanses, Claudia; Milz, Esther; Becker, Julian; Heilmann-Heimbach, Stefanie; Hoffmann, Per; Prestia, Federico A.; Galeano, Pablo; Avalos, Mariana Soledad Sanchez; Martinez, Luis Eduardo; Carulla, Mariana Estela; Azurmendi, Pablo Javier; Liberczuk, Cynthia; Fezza, Cristina; Sampaño, Marcelo; Fierens, Maria; Jemar, Guillermo; Solis, Patricia; Medel, Nancy; Lisso, Julieta; Sevillano, Zulma; Bosco, Paolo; Bossù, Paola; Spalletta, Gianfranco; Galimberti, Daniela; Mancuso, Michelangelo; Nacmias, Benedetta; Sorbi, Sandro; Mecocci, Patrizia; Pilotto, Alberto; Caffarra, Paolo; Panza, Francesco; Bullido, Maria; Clarimon, Jordi; Sánchez-Juan, Pascual; Coto, Eliecer; Sanchez-Garcia, Florentino; Graff, Caroline; Ingelsson, Martin; Bellenguez, Céline; Castaño, Eduardo Miguel; Kairiyama, Claudia; Politis, Daniel Gustavo; Kochen, Silvia; Scaro, Horacio; Maier, Wolfgang; Jessen, Frank; Mangone, Carlos Alberto; Lambert, Jean-Charles; Morelli, Laura; Ramirez, Alfredo (2019-01-31)
    Rare coding variants in TREM2, PLCG2, and ABI3 were recently associated with the susceptibility to Alzheimer’s disease (AD) in Caucasians. Frequencies and AD-associated effects of variants differ across ethnicities. To ...
  • Sex differences in demographic and clinical characteristics of psychogenic nonepileptic seizures: A retrospective multicenter international study. 
    Asadi-Pooya, Ali A.; Myers, Lorna; Valente, Kette; Restrepo, Anilu Daza; Alessio, Luciana D'; Sawchuk, Tyson; Homayoun, Maryam; Bahrami, Zahra; Alessi, Rudá; Paytan, Angélica Aroni; Kochen, Silvia; Buchhalter, Jeffrey; Taha, Firas; Lazar, Lorraine M.; Pick, Susannah; Nicholson, Timothy (2019-01-01)
    Purpose: Sex-related differences have been reported in patients with neurological and psychiatric disorders. It isalso plausible to assume that there might be differences between females and males with psychogenicnonepileptic ...
  • Congenital Zika syndrome is associated with maternal protein malnutrition 
    Barbeito-Andrés, J.; Pezzuto, P.; Higa, L. M.; Dias, A. A.; Vasconcelos, J. M.; Santos, T. M. P.; Ferreira, J. C. C. G.; Ferreira, R. O.; Dutra, F. F.; Rossi, A. D.; Barbosa, R. V.; Amorim, C. K. N.; De Souza, M. P. C.; Chimelli, L.; Aguiar, R. S.; Gonzalez, P. N.; Lara, F. A.; Castro, M. C.; Molnár, Z.; Lopes, R. T.; Bozza, M. T.; Vianez, J. L. S. G.; Barbeito, C. G.; Cuervo, P.; Bellio, M.; Tanuri, A.; Garcez, P. P. (2020-06-10)
    Zika virus (ZIKV) infection during pregnancy is associated with a spectrum of developmental impairments known as congenital Zika syndrome (CZS). The prevalence of this syndrome varies across ZIKV endemic regions, suggesting ...
  • Logistics and safety of edaravone treatment for amyotrophic lateral sclerosis: experience in Argentina 
    Quarracino, Cecilia; Bendersky, Mariana; Rey, R.; Rodríguez, G.E. (2020-05-20)
    Since 2015, edaravone is the second drug available for the treatment of Amyotrophic lateral sclerosis (ALS). In this study we analyzed the characteristics and experience of ALS patients treated with this new medication in ...
  • Percutaneous Cement Discoplasty for the Treatment of Advanced Degenerative Disc Conditions: A Case Series Analysis 
    Camino Willhuber, Gaston; Kido, Gonzalo; Pereira Duarte, Matias; Estefan, Martin; Bendersky, Mariana; Bassani, Julio; Petracchi, Matias; Gruenberg, Marcelo; Sola, Carlos (2020-08-01)
    Study design: Retrospective analysis. Level of evidence III.Objectives: To describe the results after a minimum 1-year follow-up in patients treated with percutaneous discoplasty (PD), a minimally invasive technique to ...
  • Emotional salience enhances intelligibility in adverse acoustic conditions 
    Olano, María A.; Elizalde Acevedo, Bautista; Chambeaud, Nahuel; Acuña, Andrés; Marcó, Mariano; Kochen, Silvia; Alba-Ferrara, Lucía (2020-08-19)
    Introduction: Emotion facilitates word recognition under adverse acoustic conditions. We use an auditory emotional paradigm to evaluate the ability to distinguish words from irrelevant random stimuli, elucidating its neural ...
  • CSIS: Proposal for a New Combined Screening Interpretation Score for Patients with Mild Cognitive Impairment 
    Gonzalez Aguilar, María Josefina; Alba Ferrara, Lucia (2020-12-13)
    Introduction: It is essential to have sensitive, economical and quickcognitive screening tools for early detection of Mild CognitiveImpairment (MCI). The objective of the present study was to assess anew way of interpreting ...
  • Reduced expression of the glucocorticoid receptor in the hippocampus of patients with drug-resistant temporal lobe epilepsy and comorbid depression 
    D’Alessio, Luciana; Mesarosova, Lucia; Anink, Jasper J.; Kochen, Silvia; Solís, Patricia; Oddo, Silvia; Konopka, Hector; Iyer, Anand M.; Mühlebner, Angelika; Lucassen, Paul J.; Aronica, Eleonora; Vliet, Erwin A.van (2020-07-11)
    Depressive disorders are common among about 50% of the patients with drug-resistant temporal lobe epilepsy (TLE). The underlying etiology remains elusive, but hypothalamus-pituitary-adrenal (HPA) axis activation due to ...