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Daily rhythms in right-sided and left-sided temporal lobe epilepsy

Mostrar el registro sencillo del ítem Latini, Manuel Facundo Oddo, Silvia Anzulovich, Ana Cecilia Kochen, Silvia 2023-08-16T14:23:01Z 2023-08-16T14:23:01Z 2022-04-10
dc.identifier.citation Latini MF, Oddo S, Anzulovich AC, et alDaily rhythms in right-sided and left-sided temporal lobe epilepsyBMJ Neurology Open 2022;4:e000264. doi: 10.1136/bmjno-2021-000264 es_AR
dc.identifier.other doi: 10.1136
dc.description Fil: Latini, Manuel Facundo Epilepsy, Hospital El Cruce ,Buenos Aires. Buenos Aires; Argentina es
dc.description Fil: Oddo, Silvia Epilepsy Center, José María Ramos Mejía General Hospital, Buenos Aires. CABA; Argentina es
dc.description Fil: Anzulovich, Ana Cecilia Chronobiology, UNSL, San Luis. San Luis; Argentina es
dc.description Fil: Kochen, Silvia Epilepsy, Hospital El Cruce, Buenos Aires. Buenos Aires; Argentina es
dc.description.abstract Introduction Epilepsy is closely related to daily rhythms, such as the sleep–wake cycle. The objective of this study was to evaluate the relationship between drug-resistant temporal lobe epilepsy (TLE) and the parameters related to the sleep–wake cycle, seizure time and epilepsy laterality. Methods Consecutive patients admitted to the video electroencephalogram unit with a diagnosis of TLE were enrolled. Patients were divided into two groups: those with left TLE (LTLE) and those with right TLE (RTLE). They then remained in the conditions of 12-hour light, 12-hour darkness. Demographic data, treatment, number and time of seizure occurrence, sleep diary, morningness–eveningness questionnaire, Pittsburgh Sleep Quality Index and Epworth Sleepiness Scale were recorded. Results In total, 74 patients with TLE, 43 with LTLE and 31 with RTLE, were studied. RTLE patients showed a significant preference for morningness. Patients treated with benzodiazepines showed worse sleep quality and greater daytime sleepiness. Patients who did not report any clear predominance and patients who reported seizures during wakefulness had significantly more seizures during wakefulness and patients who reported sleep predominance had more seizures during sleep (p>0.001). The LTLE group had a greater number of seizures from 8 to 16 hours, unlike the RTLE group, which had a uniform distribution (p=0.008). Conclusions This was a prospective study of patients with drug-resistant TLE performed in a controlled environment to study the impact of daily rhythms, seizure frequency and seizure distribution. Laterality seems to be a key factor in seizure distribution. es_AR
dc.language.iso es es_AR
dc.relation.ispartofseries BMJ Neurology Open 2022;4:e000264. doi: 10.1136/bmjno-2021-000264;
dc.subject temporal lobe epilepsy es_AR
dc.subject Epilepsy es_AR
dc.subject rhythmicity of epilepsy es_AR
dc.title Daily rhythms in right-sided and left-sided temporal lobe epilepsy es_AR
dc.type Article es_AR

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