ListarCentro de Medicina Traslacional (CEMET) por tema "Neoplasias Colorrectales"

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Chimeric TβRII-SE/Fc overexpression by a lentiviral vector exerts strong antitumoral activity on colorectal cancer-derived cell lines in vitro and on xenografts

Romo, Ana; Rodríguez, Tania Melina; Yu, Guo; Dewey, Ricardo Alfredo (2024-01)

The TGF signaling pathway is a key regulator of cancer progression. In this work, we report for the first time the antitumor activity of TβRII-SE/Fc, a novel peptibody whose targeting domain is comprised ...
Evaluación preclínica y estudios combinatorios de drogas de reposicionamiento en modelos experimentales de cáncer colorrectal

Sobol, Natasha T; Solernó, Luisina; Gottardo, Maria Florencia; Segatori, Valeria; Yonamine, Karina; Curvale, Cecilia; Matanó, Raúl (2021)

El cáncer colorrectal (CCR) representa un grave problema en materia de salud pública, principalmente a causa de su alta mortalidad y respuesta limitada a terapia, especialmente en estadios avanzados. En este contexto, el ...
Vasopressin Analog [V(4)Q(5)]dDAVP Exerts Cooperative Anticancer Effects in Combination With Low-Dose 5-Fluorouracil on Aggressive Colorectal Cancer Models

Sobol, Natasha T; Solerno, Luisina; Llavona, Candela; Alonso, Daniel F; Garona, Juan (2023-12)

Colorectal cancer (CRC) is a leading cause of cancer-associated mortality worldwide. Despite being an essential component of systemic chemotherapy for advanced CRC, 5-fluorouracil (5-FU) clinical use has ...

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